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DNA Translations
Posted August 17, 2004
DNA from the Beginning is now available in Italian, Danish, and Traditional Chinese! Thanks to our collaborators at the University of Padua, the National Consumer Agency of Denmark, and the National Yang Ming University, you can leggere, læse, and DNA from the Beginning. Three other language versions: Icelandic, German, and French will also be available soon.
In Memoriam
Posted August 5, 2004
Francis H. Crick, 1916 - 2004
Learn more about Crick and his work with James Watson in DNA from the Beginning: Concepts 19 and 21, and in DNA Interactive: Code.
We're hiring!
Posted May 11, 2004
Are you passionate about science? Do you know how to explain DNA to people of all ages? Can you help us develop new science curricula and activities for schools? You may be what we're looking for. The Dolan DNA Learning Center needs creative, energetic individuals with teaching experience and a science background to join our dynamic and fast-moving team. The positions have been filled.
Leadership Institute in Human and Plant Genomics
Posted March 1, 2004
Join a select group of teachers for high-level training at the DNA Boot Camp. Participants in this 3-week Leadership Institute stay on the Cold Spring Harbor Laboratory campus.
Plant workshop for college faculty
Posted March 1, 2004
Catch up with the growing field of Plant Molecular Genetics and Genomics at a 5-day workshop held at sites in Texas, South Carolina or Wisconsin. These workshops mix theoretical, laboratory, and computer work, and are funded by the NSF.
Summer faculty fellowships
Posted March 1, 2004
We are pleased to announce two faculty fellowship programs for summer 2004, both funded by the National Science Foundation. Faculty Fellows will develop educational resources in either plant genetics or bioinformatics, and will stay on the Cold Spring Harbor Laboratory campus, noted for its park-like setting and eclectic architecture. Get all of the details here.
We'd like to thank the Academy...
Posted February 27, 2004
The DNA Interactive DVD has won a British Academy of Film and Television Arts (BAFTA) Interactive Award in the factual category. The BAFTA Interactive Awards focus on a broad spectrum of the new media industry. The DNAi DVD was recognized as "An unusually rich and deep experience, stimulating personal exploration of the history, science, issues and future of the genome from the unique perspective of the people involved in its research." The award was accepted by DVD producers from The Red Green & Blue Company. Learn more about the DVD here.
Eugenics Archive grows to 2200+ items
Posted February 4, 2004
Browse 950 new photos, papers, and data – including extensive collections from noted eugenicists. Discover Francis Galton's work on fingerprint analysis and composite portraiture, and read Charles Davenport's treatise, Eugenics: The Science of Human Improvement by Better Breeding, presented in its entirety. Explore Arthur Estabrook's field photos of subjects of his (in)famous studies: The Jukes in 1915, Mongrel Virginians, and The Nam Family. Visit the Eugenics Archive home page and click the "Search the Archive" button to access the image database.
DNA Interactive Timeline
Posted January 5, 2004
2003 was a big year for DNA: the human genome sequence was completed and the 50th anniversary of the discovery of the double helix was celebrated. As you look forward into the new year, reflect back on more than 100 years of "DNA science" in the DNA Interactive Timeline. Educators can also access student activities, such as the DNAi Timeline Scavenger Hunt, by joining the myDNAi online community.
DNA: the secret of life in 5 parts
Posted December 31, 2003
The award-winning "DNA" documentary is coming soon to your TV screens! Based on the book DNA: The Secret of Life by James D. Watson and narrated by Jeff Goldblum, the five-part documentary will air in the U.S. in January, 2004. Check PBS for local broadcast dates and times. For more information on the DNA science topics covered in this documentary, don't forget to visit DNA Interactive.
Happy Holidays from the Dolan DNA Learning Center!
Posted December 22, 2003
Back by popular demand, our origami DNA activity is now in festive holiday colors. Download the template and the instructions to make your own holiday decoration. For these and other activities, register to join our online teaching community at myDNAi. Registration is free.
New arrivals in the Eugenics Image Archive
Posted December 1, 2003
Some Americans can trace their ancestry back to the Mayflower and Plymouth Rock, but there is a better chance that their forebears first set foot in America on Ellis Island. Get a feel for the immigrant experience of the early 1900s as you explore 50 newly added images collected at the archives at Ellis Island National Monument. To find these images, go to the Eugenics Archive home page, click the Search the Archive button, and then the Immigration topic link.

Watch for more new images in the upcoming weeks!
Introducing myDNAi!
Posted November 7, 2003
DNA Interactive is now even better! Register to join our online teaching community at myDNAi. Registration is free and will give you access to myDNAi features such as personalized web pages, teacher guides with student activities, and our new Lesson Builder tool. These bonus features are only available to myDNAi members. Sign up now! The DNAi web site and DVD celebrate the 50 years of DNA science since James Watson and Francis Crick's discovery of the structure of DNA.
DNA Interactive DVD
Posted November 7, 2003
This companion DVD contains more than 200 video clips and animations created for the DNA Interactive project. Eleven Nobel Laureates and more than 50 other researchers and commentators offer their viewpoints on DNA science, while spectacular 3-D animations illustrate our molecular processes. Order yours today!
Start your day with DNA!
Posted September 13, 2003
Download this Origami DNA model to fold your own paper double helix. Click here for the instructions and here to download and print the template. This DNA model and other DNA activities will be available in our DNA Interactive Teacher Guide -- coming soon!
Posted August 8, 2003
August was very good to us! DNA Interactive has won two awards: Yahoo Pick of the Day, and Macromedia Site of the Day.
Posted June 20, 2003
Examine the Chronicle of how society dealt with mental illness and other "dysgenic" traits in this final installment of DNA Interactive. Meet four individuals who became objects of the eugenic movement's zeal to cleanse society of "bad" genes during the first half of the 20th century. Then meet a modern-day heroine for a personal account of mental illness and the lesson it holds for living in the gene age. Don't forget to travel the DNA Timeline and explore Code, Manipulation, Genome, and Applications.
Posted May 30, 2003
Visit the fifth release of the new DNA Interactive web site: Applications. Investigate the many uses of DNA science. Learn more about forensic techniques, new drug development, and large-scale genomic analysis. Don't forget to travel the DNA Timeline and explore Code, Manipulations, and Genome. Watch DNAi as it grows over the next several weeks.
Posted April 11, 2003
Visit the fourth release of the new DNA Interactive web site: Genome. Leaf through the "book of life" and take a tour of the chromosomes and the genescapes of life. In video interviews, scientists discuss the mission of the Human Genome Project. And learn more about the new field of bioinformatics using our new tool – Gene Boy. Don't forget to travel the DNA Timeline and explore Code and Manipulations. Watch DNAi as it grows over the next several weeks.
Posted March 21, 2003
Visit the third release of the new DNA Interactive web site: Manipulation. Discover how techniques were developed to isolate genes and manipulate DNA. In video interviews, scientists discuss the breakthroughs that led to the ability to move or recombine DNA between species, and some of the consequences of the technological revolution ushered in by recombinant DNA. Don't forget to travel the DNA Timeline and explore Code. Watch DNAi as it grows over the next several weeks.
Posted February 28 and March 7, 2003
Visit the second release of the new DNA Interactive web site: Code. See Dr. James Watson recreate the moment in history when he worked out a key feature of the DNA double helix. Explore Code to find rare video interviews and detailed three-dimensional animations about finding the DNA structure, and cracking the genetic code. Don't forget to travel the DNA Timeline. Watch DNAi as it grows over the next several weeks.
Great summer opportunities for teachers!
Posted March 7, 2003
Enjoy a stimulating summer at a DNA Learning Center workshop. Play a role in moving biology education into the future at the DNA Boot Camp (the Pfizer Leadership Institute in Human and Plant Genomics). Or, catch up with the new field of Bioinformatics at one of six workshops held at sites nationwide. Follow the links for information and application materials. We hope to see you soon!
DNA Science: A First Course, Second Edition
Posted February 17, 2003
The book that started the revolution in biology teaching is back. This hardcover edition is updated to reflect the current state of laboratory research. DNA Science includes a highly illustrated, narrative text and 12 reliable laboratory protocols. Click here for description and purchase information.
DNA at 50: Finding the Double Helix
Posted January 28, 2003
On January 28, February 8, and 15, Nobel Laureate James Watson inspired audiences at the Dolan DNA Learning Center with his DNA at 50 public talks. See our feature videos for insight into Dr. Watson's thoughts on the DNA revolution.
Posted January 8, 2003
On display at the Dolan DNA Learning Center, you can find the first reconstruction of an adult Neandertal from fossil casts. Check out our online feature about Neandertal bones and the reconstruction process.
This installation is part of the DNALC's public exhibition: The Genes We Share.
Posted December 30, 2002
Until the genetic tests are in, there is no scientific evidence that the first human clone has been born. Check out our animation to learn how the technique works to create clones in other mammalian species.
Posted December 13, 2002
Polycystic kidney disease is a disease where cysts develop in the kidneys eventually leading to kidney failure. Learn more in Your Genes, Your Health, a multimedia guide to genetic disorders.
Posted November 1, 2002
Alzheimer disease is a progressive neurological disorder that can cause memory loss and dementia. Find out more in Your Genes, Your Health.
Posted October 9, 2002
Dr. Robert Horvitz shares the 2002 Nobel Prize in Physiology or Medicine with Drs. Sydney Brenner and John Sulston. Find out more about Dr. Robert Horvitiz's work in the process of cell death, which is a factor in the development of cancer. Click here for a short animation.
Posted September 18, 2002
Explore the many aspects of the human genome in the Dolan DNA Learning Center's new exhibition, The Genes We Share. Among the highlights: the first reconstruction of an adult Neandertal skeleton, an adaptation of the original DNA double helix model and a working automated DNA sequencer. For more information about this exhibition, click for the printable flyer.
Posted July 25, 2002
People with Down syndrome have extra genetic material in their cells. Find out how this happens in Your Genes, Your Health, a multimedia guide to genetic disorders.
Posted July 12, 2002
Tay-Sachs is an inherited disorder caused by a mutated protein called beta-hexosaminidase A. Without an active version of this protein, nerve cells die. Learn more in Your Genes, Your Health, a multimedia guide to genetic disorders.
Posted June 3, 2002
Beta-thalassemia is an inherited disorder caused by a mutation in an important blood protein. Learn more in Your Genes, Your Health, a multimedia guide to genetic disorders.
Posted June 3, 2002
How did Mendel's garden grow? Find out in this new online exhibit from the Brno monastery where Mendel spent most of his adult life.
Learn more about Mendel and other geneticists in DNA from the Beginning, an animated primer on genetics and molecular biology.

Posted May 2, 2002
May 2nd marked the 75th anniversary of a nadir in American law and society. On this day in 1927, the United States Supreme Court upheld the concept of eugenic sterilization for people considered genetically "unfit."

Learn more about this decision, visit our Eugenics archive.

Posted April 2, 2002
Hemochromatosis is a condition that causes the body to absorb too much iron. This can lead to serious organ damage. Hereditary hemochromatosis is a recessive disorder. Find out more in Your Genes, Your Health, a multimedia guide to genetic disorders.
Posted March 18, 2002
Sickle cell is a recessive disorder. People with sickle cell have a mutation in a blood protein that changes the shape of their hemoglobin cells. Find out more in Your Genes, Your Health, a multimedia guide to genetic disorders.
Posted February 25, 2002
Neurofibromatosis refers to two genetically distinct dominant disorder – NF1, NF2. People with neurofibromatosis develop tumors in their nerve tissue. Find out more in Your Genes, Your Health, a multimedia guide to genetic disorders.
Posted February 5, 2002
What is it like to be present when history is in the making? Thanks to a diary entry, we have an account of the "unveiling" of Watson and Crick's DNA helix model at the Cavendish Laboratory on April 1953. Read more about this event and the "great air of excitement" it generated.
Posted January 28, 2002
is an inherited dominant disorder caused by an expanded version of the huntingtin gene. People with Huntington lose cognitive and motor functions as their neurons degenerate. Find out more in Your Genes, Your Health, a multimedia guide to genetic disorders.
Posted January 3, 2002
is an inherited recessive disorder caused by a defect in a metabolic enzyme. People with PKU accumulate phenylalanine, which can damage neurons in the brain. Find out more in Your Genes, Your Health, a multimedia guide to genetic disorders.
Posted December 11, 2001
is an inherited sex-linked disorder. Boys with Duchenne muscular dystrophy or the milder form Becker, lose muscle cells because of a defect in the dystrophin gene. Find out more in Your Genes, Your Health, a multimedia guide to genetic disorders.
Posted November 13, 2001
Our award winning web site DNA from the Beginning is now a 3 CD-ROM set. You've used it online, now own it yourself! Buy it online now.
Posted November 13, 2001
is a recessive disorder affecting the cellular channels that transport salt ions. This leads to the formation of thicker mucus around lung and pancreatic tissues, which can cause respiratory and digestive problems. Find out more in Your Genes, Your Health, a multimedia guide to genetic disorders.
You will need the Macromedia Flash Player and Quicktime Player.
Alan Alda greets his genes at the Dolan DNA Learning Center!
Posted October 16, 2001
Want to try the lab Alan Alda did on The Gene Hunters? Go to the Alu section of our Genetic Origins site. The entire lab with the theory, protocols, and exercises are online. Try it with your science class!
On October 23, 2001, 9 PM, PBS's Scientific American Frontiers will premiere The Gene Hunters. The show features interviews with Cold Spring Harbor Laboratory's Dr. James Watson and Dr. Tim Tully. Also, not to be missed is Alan Alda's "Fun with DNA" experience with our own Scott Bronson.
Posted October 9, 2001
Hemophilia is a sex-linked disorder that can cause uncontrolled bleeding episodes. Find out more in Your Genes, Your Health, a multimedia guide to genetic disorders. This site was chosen as a Yahoo site of the week.
You will need the Macromedia Flash Player and Quicktime Player.
Yeast Cell Researcher's Rise to Fame
Posted October 9, 2001
Dr. Leland Hartwell, of the Fred Hutchinson Cancer Research Center in Seattle, shares in the 2001 Nobel Prize for medicine. Learn about his work on the cell cycle in DNA from the Beginning: Concept 38.
You will need the Macromedia Flash Player.
And the winner is ...
Posted October 1, 2001
Dr. Mario Capecchi shares this year's Albert Lasker Award for basic medical research. Many of those who win the Lasker are pioneers in their field and go on to win other prizes and awards.
Find out what makes Dr. Capecchi's revolutionary work so important by reviewing our animation in DNA from the Beginning, Concept 41: DNA is only the beginning for understanding the human genome.

You will need the Macromedia Flash Player.
Cloning 101
Posted September 7, 2001
The ability to create a clone used to be science fiction. Dr. Ian Wilmut's group changed that in 1997 with the creation of Dolly the sheep. Since then the debate on applying the technique to clone human beings has been ongoing.
Based on all the discussion, it may sound like cloning, human or otherwise, is an easy process. Find out what is actually involved in the cloning process by viewing our short animation.
Stems of Controversy
Posted July 31, 2001
Unless you have cut yourself off from all media, you have heard the term "stem cells" in the news quite a lot recently. Embryonic stem cells have the potential to become any cell in the body. Research using these cells may eventually lead to therapies that replace damaged cells and help people with Alzheimer disease, spinal cord injuries, heart disease, and other conditions. Embryonic stem cells were isolated two years ago, and scientists are still working to uncover their secrets. Find out how these cell lines are generated in this short animation.
Posted July 24, 2001
The "stones and bones" of archeology have been complemented with DNA analysis. In addition to fossils and other artifacts, scientists use mitochondrial DNA to work out the evolutionary history and migration patterns of modern humans.
Find out how this is done in the Mitochondrial Control Region section of our Genetic Origins web site. After you learn the theory behind mitochondrial DNA analysis, click the Media/Animation link to see an interview with Dr. Svante Paabo, the scientist who successfully isolated Neandertal DNA. Then, use what you've learned to solve the Mystery of the Neandertal and the Mystery of the Romanovs.
The Face of America
Posted July 9, 2001
Millions of Americans are descendants of immigrants who came to the United States in the early 1900s. See our virtual exhibit on Immigration Restriction and find out how the American eugenics movement restricted the influx of immigrants in the 20th century. To find out more about the American Eugenics movement, access our website.
Driving for DNA
Posted June 25, 2001
The 8th Annual Golf Tournament, held at the Piping Rock Country Club, was a rousing success. Local business leaders were participants in the fundraising event. NY Islander great Clark Gilles and News 12 anchor Scott Feldman also attended the festivities. Sponsored by the Corporate Advisory Board, the event is the largest source of unrestricted income for the Dolan DNA Learning Center. For more on the day's events, click here.
Dedicated to DNA

Posted June 12, 2001
The Dolan DNA Learning Center was dedicated during a ceremony held on June 8, 2001. Dr. Peter Bruns of the Howard Hughes Medical Institute (at right) was the keynote speaker. Charles and Helen Dolan (left and center) of the Dolan Family Foundation also addressed the 100 invited guests.

To see results of the year-long construction and renovation process, click here.

Posted May 13, 2001
Marfan syndrome is the second disorder to be featured on Your Genes, Your Health, our multimedia guide to genetic disorders. Marfan syndrome affects the connective tissues of the body and can be a serious health risk. Your Genes, Your Health is an ongoing project funded by the Josiah Macy, Jr., Foundation. Additional disorders will be added on a regular basis.

This site requires Flash Player® and QuickTime Player(TM). (Click on the links for free downloads.)

Posted April 2, 2001
Introducing our new web site!
Your Genes, Your Health is a multimedia guide to human genetic disorders. It uses animations and videos to provide innovative explanations of genetic disorders affecting millions of people worldwide. The first featured disorder is Fragile X Syndrome, the most common inherited cause of mental impairment. This web site is an ongoing project and additional disorders will be added to this site on a regular basis.

Many thanks to the Josiah Macy, Jr., Foundation for funding this project. This site requires Flash Player® and QuickTime Player(TM). (Click on the links for free downloads.)

Teacher Workshops

Posted March 19, 2001
Teach all that you can teach.
DNA Boot Camp
Bioinformatics
Wow your students in the Fall with new cool labs.

Posted March 5, 2001
Visit Cold Spring Harbor Laboratory's web site and see a virtual exhibit on its history. The First 100 Years was produced for the Lab's 1990 centennial, and is now available online. Find out how the world-famous research laboratory started as a "summer camp" for scientists.
Great Experiments
Posted February 13, 2001
The Human Genome has been sequenced and the results have been published (February 15th). What now? Find out how scientists are using the data from the human genome project to figure out what the genes actually do. Learn about "gene targetting" in concept 41 of DNA from the Beginning.
Great Experiments
Posted January 29, 2001
Cells have a programmed life cycle; some cells are even programmed to commit suicide. Find out why programmed cell death is an important concept in cancer cell research. Visit Concept 38 in DNA from the Beginning. Dr. Scott Lowe, featured in Concept 38, recently published his results in Nature. Read about his findings here.
Posted January 15, 2001
The 1927 Buck v. Bell Supreme Court decision allowing the sterilization of the "feeble-minded" has never been overruled. See our virtual exhibit on how this came to be, and how eugenical "studies" were used to support this judgement. Visit our eugenics archive to learn more.
Ever Wonder?
Posted January 2, 2001
Start the New Year right! Learn about "the most significant human achievement since the moon landing." Find out about the people, the strategies, and the techniques in the Human Genome Project in Concept 39 of DNA from the Beginning.
Happy Holidays!

Posted December 21, 2000
After the celebrations, find out how genes can be turned on and off like Christmas lights. Check out DNA from the Beginning -- Concept 33. Genes have switches too.

DNA from the Beginning
has come to the end!
Posted December 1, 2000
In this final set of concepts, learn about gene expression and control, the human genome project, cell cycle, and other innovations in molecular biology and genetics. Many thanks to the Josiah Macy, Jr. Foundation for funding this project.
Posted November 21, 2000
View this lecture by Dr. James Watson, President of Cold Spring Harbor Laboratory. Dr. Watson recounts events that led up to the discovery of the double helix structure of DNA in 1953. The lecture was first given at Cold Spring Harbor Laboratory on November 2, 1999.
Eugenics Featured in Nature Reviews
Posted November 15, 2000
DNALC Director David Micklos and Professor Elof Carlson coauthored an article for this new journal. Click here to read the article in the online issue. Click here to view a PDF file of the article.
Posted November 1, 2000
Introducing our new web site! Students can use their own DNA "fingerprints," from mtDNA or Alu polymorphic data, as starting points in the study of human evolution. Two labs with instructions and recipes are available.
Posted October 16, 2000
In higher organisms, genes are stored as coding (exons) and non-coding (introns) sequences. Find out about "split" genes in Concept 24 in DNA from the Beginning.

Posted October 1, 2000
What are the problems with eugenics as a "science?" Find out in our virtual exhibit written by Garland Allen from Washington University, and visit our eugenics archive for more information.

Posted September 11, 2000
Where did "life" molecules like RNA, DNA, and proteins come from? What kind of conditions would planets need to start life? Find out in Concept 26 of DNA from the Beginning.
Posted August 22, 2000
What is eugenics, and why was it so popular at the beginning of the 20th century? See our virtual exhibit on Eugenics Popularization. Also visit our Eugenics Archive to learn more.

Posted August 1, 2000
Boris and Natasha beware! This year's Intel Science Talent Search winner, Viviana Risca, will foil your dastardly plans to intercept Rocky and Bullwinkle's secret messages! And she'll do it with DNA.
Posted July 5, 2000
What is the "genetic code"? How does the cell process the information encoded in our DNA? Find out how they "cracked" the code in Concept 22 of DNA from the Beginning.
Posted June 27, 2000
The Human Genome is now available! Find out what a "rough" draft means, and what needs to be done to interpret the information encoded in our genes.

(Also, to learn how DNA is sequenced, see our animation.)
Posted May 30, 2000
Free Public Lecture: June 26, 2000 at 7 PM. Viviana Risca, Intel Science Talent Search winner, and Laura Landweber, Princeton University, will talk about using DNA as a "computer" code. Bring your secret decoder ring!
Posted May 16, 2000
Millions of people immigrated to the United States in the early 1900s. See our virtual exhibit on Immigration Restriction. Find out how the American Eugenics movement restricted the influx of immigrants in the 20th century. Click here to visit the Eugenics Archive.

This is one of nine virtual exhibits at our Eugenics site. Macromedia Flash player is needed for viewing.

Posted May 1, 2000
Thanks to a generous gift from the Dolan Family Foundation, construction has begun on a new addition to our 1925 Georgian schoolhouse. Check our construction page for regular updates on how the work is progressing.

Posted April 17, 2000
How is DNA sequenced anyway? What is the chemistry behind the technique used in the Human Genome Project? Find out in Concept 23 of DNA from the Beginning.

Posted April 3, 2000
What did Watson and Crick do to win their Nobels? Get the full animated story of how they figured out the 3-D structure of DNA in Concept 19 of DNA from the Beginning. April 6th, 2000 was Dr. Watson's 72nd birthday.

Posted March 20, 2000
The ability to clone animals from adult cells is no longer science fiction, but science fact. In this feature article, see how cloning works in the animation, and read about how cloning will affect our futures.
Dr. Alan Kay is giving a lecture entitled "Origins of the Personal Computer -- and Beyond" at Cold Spring Harbor Laboratory on Sunday, November 22, 1998. Follow this link for more information.
Genes, Teens, and the World Wide Web will examine the use of networked, multimedia technologies in biology education. This meeting will take place at the Cold Spring Harbor Laboratory's Banbury Conference Center over November 22-24, 1998.

DNA Fingerprinting

The ability to dissect with pinpoint accuracy an individual's genetic material has revolutionized the criminal and forensic communities. In this Gene Almanac exclusive, read about the science behind the technology and how these tools are used inside the courtroom.